![]() ![]() In intermaxillary traction the percentage of initial force remaining after 48 hours was 61%. A continuous significant force drop in all elastics was seen at all time intervals (P . Fifty percent of the force was lost after 3.9 hours for the medium elastics and after 4.9 hours for the heavy elastics. The force amounts were measured and compared at different time intervals. Fifty-two orthodontic patients wearing fixed appliances using Class II elastics were asked to wear premeasured- force 3/16-in heavy and medium intermaxillary elastics. Our objectives were to assess the force degradation of orthodontic latex elastics over 48 hours in vivo and to study the relationship between the amount of mouth opening and the degree of force decay. Qodcieh, Sadeq M Adel Al-Khateeb, Susan N Jaradat, Ziad W Abu Alhaija, Elham S J Forced degradation studies on aloe emodin and emodin gives information about its storage and intrinsic stability conditions considering the advanced pharmaceutical aspects of formulation.įorce degradation of orthodontic latex elastics: An in-vivo study. Aloe emodin, was more susceptible to acid hydrolysis and degradation was found to a lesser extent under thermal degradation whereas significant degradation was observed under acid hydrolysis, lesser extent was observed under alkali hydrolysis for emodin. Both aloe emodin and emodin were subjected to various forced degradation studies such as oxidation, acid and alkaline hydrolysis, photolysis, hydrolytic and thermal degradation. The present work was to observe the effect of different forced degradation conditions by high-performance thin layer chromatography on potential markers i.e. ![]() They are abudant in plants like candle bush, aloes, cascara bark and rhubarb. ![]() Narayanan, Sindhu Jadhav, Aruna P Kadam, V JĪnthraquinones are natural phenolic compounds, which are reported to act as anti-aging, anti-inflammatory, antioxidant, anti-cancer, laxative and antitumor agents. In this chapter, we provide detailed methods for forced degradation analysis under thermal, light, and mechanical stress conditions.įorced Degradation Studies of Aloe Emodin and Emodin by HPTLC. In addition to supporting the development of analytical methods for the detection of degradation products, these stress studies are used to identify optimal long-term storage conditions and are part of the regulatory requirements for the submission of stability data. Hasija, Manvi Aboutorabian, Sepideh Rahman, Nausheen Ausar, Salvador Fĭuring the early stages of vaccine development, forced degradation studies are conducted to provide information about the degradation properties of vaccine formulations. Practical Approaches to Forced Degradation Studies of Vaccines. ![]()
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